Birth defects are estimated to affect more than 120,000 children in the United States every year. About 3% of babies, or 1 of every 33, are born with a structural birth defect. Birth defects are one of the leading causes of infant deaths and illness. Babies born with birth defects have a greater chance of illness and long-term disability than babies without birth defects. Babies with birth defects are also more likely to be born preterm (before the 37th week of pregnancy) than babies without birth defects. Birth defects account for approximately 30% of all pediatric hospital admissions. Most birth defects are thought to be caused by a complex mix of genetic, behavioral, and environmental factors, although, for many birth defects, exactly how these factors work together is unclear.
More research is needed to study the subtle links between environmental hazards and birth defects, which is why birth defects are an important part of the Environmental Public Health Tracking Network. In summary, birth defects are expensive and burdensome conditions that need to be reduced through better tracking, research and prevention. The risk of certain birth defects can be reduced by following the recommendations below.
Birth Defects and the Environment
Although some research on how environmental hazards might cause birth defects has been done, much more work is needed to understand the relationship between the environment and birth defects. Doctors and public health scientists know how some birth defects happen and in some cases can make recommendations to help prevent them. But the causes of many other birth defects are unclear. Analyzing data about when and where birth defects happen will help scientists understand whether these defects might be related to the environment.
It is not clear how many birth defects are related to exposure to environmental hazards, such as pollution, toxic chemicals, and ionizing radiation. Some endocrine-disrupting chemicals, including polychlorinated biphenyls (PCBs), chlorine-related dioxins, and pesticides, have been linked to nervous system defects and developmental problems such as reduced muscle tone and response. Exposure to disinfection by-products in drinking water, such as trihalomethanes (THMs), may also increase the risk of some types of birth defects which affect the brain and spinal cord, the urinary tract, and the heart. In addition, living near a hazardous waste site has been identified as a possible risk factor for birth defects, such as neural tube defects which are defects in the development of the brain and spinal cord, and heart and blood vessel defects.
- Mother's Age
Women over the age of 35 years have a higher chance of having a child with Down syndrome than women who are younger. Read more about Down syndrome. Teenage mothers are more likely to have a baby born with gastroschisis -- a defect in the abdominal wall.
Women who smoke and use alcohol while pregnant have a higher risk of having a baby with certain birth defects. Also, if a woman takes certain medications or drugs during her pregnancy, the chance of birth defects in her offspring is increased.
Some birth defects are caused by genetic problems. Sometimes, these birth defects run in families, but other times they will occur even when there is no one else in the family who has this problem. If you have concerns that your baby may be at risk of having a genetic abnormality, you can talk with a clinical geneticist or genetic counselor.
To Have a Healthy Pregnancy and a Healthy Baby
You can do many things to help yourself have a healthy pregnancy and a healthy baby:
- Plan your pregnancy
- See your health care provider before you become pregnant.
- Control any medical condition (obesity, diabetes, seizures, etc.) before getting pregnant.
- Take a vitamin with 400 micrograms of folic acid daily before and during pregnancy.
- Take care of yourself
- Get plenty of rest.
- Exercise moderately.
- Eat a well-balanced diet.
- Avoid contact with chemicals and other things in the home and workplace that may harm an unborn baby.
- Avoid alcohol, tobacco, and street drugs.
- Talk with your health care provider before taking any over-the-counter drugs.
- See your healthcare provider
- If you are planning to get pregnant or you are already pregnant, one of the most important things you can do is see your health care provider. Prenatal (before birth) care can help find some problems early in pregnancy so that they can be monitored or treated before birth. Some problems might be avoided with prenatal care.
- Not all birth defects can be prevented, but you can take some actions that increase your chance of having a healthy baby. Many birth defects happen very early in pregnancy, sometimes before you might know that you are pregnant. Remember that about half of all pregnancies in the United States are not planned.
Birth Defects Data
The EPHT Program is tracking the total number of cases for 12 specific birth defects:
- Spina bifida (without anencephaly)
- Hypoplastic left heart syndrome
- Tetralogy of Fallot
- Transposition of the great arteries (vessels)
- Cleft lip with or without cleft palate
- Cleft palate without cleft lip
- Upper limb deficiencies
- Lower limb deficiencies
- Trisomy 21
- Among mothers 18-<35 years of age at delivery
- Among mothers 35-59 years of age at delivery
For more information about birth defects data for environmental public health tracking
For more information on birth defects: